Lioresal is a muscle relaxant of central action. Its major constituent is Baclofen. When decreasing the excitability of afferent sensory end sections of the fibers and suppressing the intermediate neurones, depresses mono-and polysynaptic transmission of nerve impulses. It reduces the pre-stressing muscle spindles. It has no effect on neuromuscular transmission. When neurological ailments go with spasticity of the skeletal muscles, decreases the painful spasms and clonic convulsions. It also enhances the range of motion in joints, facilitates passive and active kinesitherapy.
This preparation has the following contraindications:
Being a preparation with powerful action, this preparation may induce some undesirable effects. Among them may happen:
The preparation must be administrated inside, while having a meal. The starting dosage is 5 mg 3 times per day with the subsequent increase in the dosing every 3 days at 5 mg to achieve the effect; the maximal dosage is 100 mg / day (for a short time in the hospital).
Adverse effects are commonly ephemeral and should be distinguished from the symptomathology of the ailment that is about being cured. With concomitant epilepsy the curing runs without the abolition of anti-epileptic drugs. In examinees with liver ailment and diabetes there should be periodically monitored the work of "liver" transaminases, alkaline phosphatase, glucose.
Information about this preparation contained is given for medical and pharmaceutical professionals and should not be used for self-curing. The information is presented for reference and cannot be regarded as official.
Remember! Self-curing is dangerous and may induce unwanted effects that can do severe harm to your health.