The preparation belongs to centrally acting muscle relaxants. It is an analogue of GABA (gamma-amino butyric acid) which is a natural mediator involved in inhibition of nerve impulses in the central nervous system (brain and spinal cord). The preparation includes material baclofen.


Indications for the Usage

Lioresal is appointed to cure the following ailments of the spine:


Lioresal should not be taken while the following illnesses and conditions:

The Principle of Operation

Lioresal Baclofen Lioresal bloodstream reaches the spinal cord, its GABA receptors. There it suppresses specific reflex reactions that can block the transmission of excitation along the nerve endings. As a result, there is a reduction in muscle tonus, reduction of single twitch muscles, reduce pain, normalization of movement in the spine. Also, the drug helps to normalize sleep and work the pelvic organs, if the problems are caused by diseases of the spine.


As a special action Lioresal has a sedative (sedative) action, up to and a few sleepy depresses respiratory function. This should be taken into account when driving the vehicle, and the presence of diseases of the respiratory system.



Lioresal in the form of a solution for intrathecal

Lioresal injection is carried out in the spinal cord through a special catheter or by a puncture in the lumbar spine. Other modes of administration are contraindicated. Before the introduction of the basic drug dosage should be done tolerance test drug in the minimum dosage that the doctor selects individually.


Maintenance dose averages 300-800 micrograms each day. The maximum can be administered up to 2000 mg per day. The dosing for children is lower.

In the form of tablets

Baclofen 3d formula Lioresal tablets should be taken by mouth, with food. Initial dosage is 5 mg 3 times a day. Every three days, the daily dosage is increased by 5 mg. The maximum daily dose is 100 mg. The average therapeutic dose is 30-75 mg per day. Duration of treatment the doctor chooses a strictly individual. Discontinuation of treatment is carried out gradually over 1-2 weeks.


Children from 4 to 10 years are appointed to take 30-60 mg each day, divided into 2-3 doses. The adults should begin the curing with 10-15 mg per day, gradually increasing the dosage. Discontinuation of treatment is carried out for 2 weeks.


Adverse effects

Adverse effects of Lioresal include the following features:


Lioresal cannot be appointed during pregnancy. In the period of lactation you should temporarily discontinue breastfeeding.


For children up to 4 years it is also contraindicated. From 4 to 12 the preparation should be taken under strict medical supervision and strict compliance with dosage.


Alcohol is not compatible with the reception Lioresal.


During curing with this preparation driving motor vehicles is prohibited.


Note! Self-curing is unsafe for you and may harm your health.